While there have been a number of Legendary Pokémon to this point, Mewtwo was the ultimate original Legendary. Sure, the original 151 set had Zapdos, Moltres, Articuno, Mew, and some pseudo-legendary Pokémon such as Dragonite. None others though were designated as the strongest Pokémon.
With that kind of hype, it’s no surprise that Mewtwo has some incredibly popular and expensive Pokémon cards following its legend. And that’s exactly what we are going to cover here today.
Take note that this list will be sorted by average raw value. I will include PSA 10 values as well, but will keep the list based on raw value as it is a more “real” value in case you find one of these lying around. Some of these cards also have several variants (Japanese, 1st Edition, Promo, etc) that I will separate and include on the list.
*Please note that this article was updated in May of 2026 and prices for some of these cards may have fluctuated in price since then.*
Without further ado then, let’s check out the 20 most expensive Mewtwo Pokémon cards!
#20 – Mewtwo #12
Raw: ~$145 | PSA 10: ~$4,210
Our first Mewtwo on the list is a vintage Mewtwo from the Delta Species set. It is far from the most expensive card in the set, but still holds a special place in peoples hearts.
Next to some of the more modern Mewtwo Pokémon cards, this one is really a steal.
#19 – Armored Mewtwo #SM228
Raw: ~$150 | PSA 10: ~$6,000
Next up is an incredibly unique Armored Mewtwo, which was could be found in the Fall 2019 Collectors Chest. The Japanese version though (which is much cheaper)could be picked up if you went to see the Mewtwo Strikes Back movie release.
Because of the print quality of these, PSA 10’s were hard to come by and have an impressive $6,000+ price tag.
#18 – Mewtwo & Mew GX #SM
Raw: ~$270 | PSA 10: ~$1,200
The Mewtwo & Mew GX is both a cool and a highly entertaining card. It has been a fan favorite since release as a lot of Tag Team cards are.
If you like the combo but not the price, there are a number of different versions at ~$130, ~$90, and less if you are interested in Japanese versions.
#17 – Mewtwo VSTAR #GG44
Raw: ~$280 | PSA 10: ~$600
The Mewtwo VStar is an absolute stunner of a card. Not only is it a mirror card to the Charizard VStar #SWSH262, but it has rocketed up in price since January of 2025, becoming one of the most expensive VSTAR Pokémon cards of all time.
#16 – Mewtwo & Mew GX #242
Raw: ~$305 | PSA 10: ~$1,040
If you like Rainbow Rare Pokémon cards, the Mewtwo & Mew is one of the best. What started off as two of the most powerful and conflicting Pokémon in the franchise now share a number of cards together.
And in rainbow form? Tell me you don’t want to add this one to the collection.
#15 – 1st Edition Rocket’s Mewtwo #14
Raw: ~$330 | PSA 10: ~$6,665
Feast your eyes on one of the original Mewtwo Pokémon cards. The 1st Edition Rocket’s Mewtwo. Coming in at a respectable #15 most expensive, the Gym Challenge Mewtwo is both rare and incredibly popular in the Gym series sets.
As you may have imagined, there is a non 1st Edition for quite a bit cheaper in case this one is out of your price range. It is a beautiful card regardless of which one you own.
Despite there being other more expensive Rocket’s Mewtwo’s, let’s not forget their origins with this beauty above.
#14 – Team Rocket’s Mewtwo ex #125
Raw: ~$350 | PSA 10: $825
The next Mewtwo on the list is the Japanese Team Rocket’s Mewtwo from the Glory of Team Rocket set (the Japanese version of Destined Rivals).
Despite it being a more modern card, the Team Rocket’s Mewtwo quickly blew up in price and has not settled down one bit.
If you like the card but don’t want to shell out that much, there is a cheaper Team Rockets Mewtwo available that might satisfy.
#13 – Mewtwo Expedition #20
Raw: ~$370 | PSA 10: $5,630
Coming in at #13 is the #20 Holo Mewtwo from the Expedition set. While this card still has a respectable raw value, its PSA 10 value is astonishingly high at nearly $6,000! The cards from the “E-Reader” Pokémon card sets actually had a scanning function, which made most of them heavily played with. Because of that, these cards are incredibly hard to find in pristine condition.
In case you were curious of the actual number, only 59 PSA 10’s are in existence as of 1/1/2025. In case you weren’t sure, that is a very low PSA 10 population for any card.
If you like Mewtwo and want to add more to your collection, there is also a reverse holo version of this card that sells for about $300!
#12 – Team Rocket’s Mewtwo Ex #281
Raw: ~$440 | PSA 10: 1,390
Tired of Team Rocket’s Mewtwo? Didn’t think so. Feast your eyes on the Ascended Heroes version of it.
While the Dragonite, Gengar, and Pikachu in the Ascended Heroes set outshine the Team Rocket’s Mewtwo, it’s hard to deny how cool the Mewtwo is.
I think the only way to decide which Team Rocket’s Mewtwo is cooler is to buy them both and keep them in a binder next to eachother. You’re welcome.
#11 – Mewtwo Prerelease Staff #51
Raw: ~$465 | PSA 10: ?
The Mewtwo Prerelease Staff might not be very known to a lot of you. That’s because this particular Mewtwo was only given out to staff members who helped with pre-release events. Therefore, a lot of these cards fell to shop owners and were incredibly limited in quantity.
To give you an idea of how rare they are, there are only 5 of these cards in PSA 10 with none registered as sold. The PSA 10 price then is still up in the air.
Once again, there are alternative options to get a very similar card to this one without the huge price tag. The Prerelease (non staff) version of this card runs for about $250. If that’s still too pricey, you can get the standard Evolutions Mewtwo for just a couple of dollars.
#10 – Japanese Mewtwo GX #82
Raw: ~$475 | PSA 10: ~$3,770
The Japanese Mewtwo GX from the Shining Legends set is an instant classic.
The Mewtwo being kept inside a container depicting its origins was a big change from the art of previous Mewtwo Pokémon cards. Add that into the rarity of this and it quickly became a massively popular Mewtwo almost overnight.
Like the Japanese version but want an English version as well? Keep scrolling…
#9 – Mewtwo Reverse Holo #29
Raw: ~$520 | PSA 10: ~$5,200
If you haven’t heard of the Legendary Collection set, you are in for a treat. The Reverse Holo Mewtwo from the aforementioned set has one of the best holo patterns of any set ever. And to have Mewtwo as the centerpiece makes it all the better.
The reason for the sizeable PSA 10 price tag is that these Legendary Collection cards were incredibly hard to grade well. Their holo pattern themselves did not always print well and can be scratched easily. Because of that, there are only 51 of these cards in PSA 10 as of writing this article.
If you like the art but the cost is a little too high, fear not. There is a non-holo version of this Mewtwo from the Legendary collection as well as a Black Star Promo with the same art for much less than the above.
And if you have it in your collection already? Then I am simultaneously happy for you and jealous of you.
#8 – Mewtwo GX #78
Raw: ~$525 | PSA 10: ~$7,400
For those who wanted the English version of this Mewtwo, here you go.
Despite the Mewtwo GX from the Shining Legends set being released in 2017, it quickly became an incredibly sought after card in all of the Sun & Moon series. Not only did the card have an incredibly tough pull rate, but it also was great in competitive TCG play.
Regardless if you play the Pokemon Trading Card Game or just like to collect, this Mewtwo is absolutely one that is worth picking up!
#7 – Japanese Mewtwo Gold Star #2
Raw: ~$540 | PSA 10: ~$11,040
Coming in at #7 is the Japanese Gold Star Mewtwo. If you don’t know about Gold Star Pokémon cards, they are now some of the most valuable and sought after Pokémon cards there are. Fortunately, Mewtwo got to be one of these iconic cards.
While not all Gold Star Pokémon cards are holo, the Japanese Mewtwo does have an incredible purple space like holo sheen. This background also shows off the out of the frame Mewtwo in all of its glory.
For reference on the pricey PSA 10 number, there are about 300 PSA 10’s in existence for this card.
#6 – Team Rocket’s Mewtwo ex #231
Raw: ~$550 | PSA 10: ~$1,450
Coming in at #6 is the last modern Mewtwo on the list. The Team Rocket’s Mewtwo ex from the Destined Rivals set.
Despite being from a more recent set than the original Rocket Mewtwo above, its rarity and popularity quickly exploded upon release in May 2025.
While its PSA 10 price isn’t as impressive as others on this list, its raw price puts it as a top 10 raw Mewtwo ever.
#5 – 1st Edition Shadowless Base Set Mewtwo #10
Raw: ~$680 | PSA 10: ~$49,630
The #5 most expensive Mewtwo on the list is the first English Mewtwo Pokemon card to ever be released. With only 82 PSA 10’s in existence, this card commands an impressive PSA 10 number.
The case could (and probably should) be made that this is the most iconic Mewtwo ever. Despite only being #5 on this list, it is the true English original and should be a major chase for any Mewtwo lover.
If you love the card but not the price, there are fortunately some cheaper alternatives with a slightly lower price available. The Shadowless Mewtwo is the closest to the 1st Edition in color, look and otherwise and is between $80-$150. The original Base Set Mewtwo doesn’t quite have the same coloring but can get you a very similar card for between $15-$50.
#4 – Japanese Shining Mewtwo #150
Raw: ~$470 | PSA 10: ~$9,100
Coming in at the #4 most expensive Mewtwo is the Japanese Shining Mewtwo. Similar to its English version which hasn’t been discussed yet… the Japanese Shining Mewtwo also shows the holo on the Mewtwo itself rather than the background. This gives Mewtwo an “aura” that best suits Mewtwo over arguably any other Pokémon.
Outside of the art though this Japanese set was only released in 1st Edition and was incredibly rare and tough to pull. As of writing this article, the Japanese Shining Mewtwo has only 74 PSA 10’s. Its last sold was more than a year and a half ago at $9,100, which means its current price is probably far higher than that.
#3 – Shining Mewtwo #109
Raw: ~$775 | PSA 10: ~$36,000+
Coming in at #3 is the Shining Mewtwo from the Neo Destiny set. The Neo Destiny set was the first Pokémon card set to switch up the holo and put it on the Pokémon itself rather than just the background, same as the Japanese version above.
While Charizard sits atop the most expensive in the set, the Shining Mewtwo falls closely behind it as the next most expensive. And if there were ever a Pokémon to show off this holo, it’s most definitely Mewtwo.
While we don’t know what the PSA 10 Japanese version is above, the last two sold English versions sold for $36,000 and $45,000!
#2 – Mewtwo Gold Star #103
Raw: ~$1,680 | PSA 10: ~$55,000-$85,000
Coming in at #2 is the English Gold Star Mewtwo from the Holon Phantoms set. Much like its Japanese counterpart (#7 on the list), it has a space-like holo background and shows a “shiny” version of Mewtwo that has a slightly different color than the original.
While this is an older card, it was one of the earlier cards that showed the Pokémon going outside of the edges of the border, which gives this a great 3D perspective.
Let’s be real though, regardless of your thoughts on the art, this card holds an impressive $1,600 average raw value and a most recent sold $85,000 PSA 10 price tag!! This card only has 123 PSA 10s in existence and is the most expensive PSA 10 by a longshot.
#1 – 1st Edition Shining Mewtwo #109
Raw: ~$2,000 | PSA 10: ~$22,000-$40,000
The most expensive raw Mewtwo Pokémon card is none other than the 1st Edition Shining Mewtwo #109 from the Neo Destiny set. Averaging an incredibly impressive $2,000, this card is only second in the entire set to the 1st Edition Shining Charizard.
Despite having a lower PSA 10 value than the gold star Mewtwo, the raw value trounces everything on this list by a pretty substantial amount. Regardless of which you prefer, there are no wrong answers here.
If you are trying to pick this card up, be careful out there as this card does have fake versions.
Conclusion
How can you not like Mewtwo? It’s one of the original 151 Pokémon and has stayed one of the strongest and most interesting through 9 entire generations of Pokémon. Because of that, Mewtwo has some incredibly interesting, diverse, and valuable Pokémon cards in the market.
Hopefully you enjoyed looking through this list! If you’d like to add any commentary or feedback, shoot me an email at info@pokecardguy.com!
Interested in the most expensive Pikachu Pokémon cards? You might be surprised at how valuable they are.
What about the most expensive Charizard Pokémon cards? It’s a pretty impressive list.
Thanks for reading!